As part of the NIA ITP federally-funded program that examines treatments with the "potential to extend lifespan and delay disease and dysfunction," and thereby extend lifespan, researchers provided the supplement Protandim®, the Nrf2 Synergizer® to male mice in a rigorous and carefully controlled study. The result: Protandim was proven to "significantly increase the lifespan of male mice, with a 7 percent increase in median survival." The findings on female mice were less dramatically conclusive, showing an increase in lifespan of 3 percent.
Since the NIA ITP program's inception in 1999, Protandim is the only nutritional supplement tested that has been proven to increase the median survival in mice, thus delaying the aging process.
Protandim was chosen for testing based on positive indications on its ability to suppress tumor-promoting oxidative stress, cell proliferation and inflammation, and the ability to protect the heart from oxidative stress and fibrosis in studies published prior to 2010. Some of the other recognized nutritional substances tested included fish oil, curcumin, green tea and resveratrol. None of these individual ingredients were shown to increase the lifespan of mice.
"We are extremely excited about these results from the NIA ITP study and are enthusiastic about the continued advancement of the research and findings that demonstrate Protandim's veracity and effectiveness in additional studies to come," said
For more information about the Protandim results in the NIA's study, readers can click here or visit: http://onlinelibrary.wiley.com/doi/10.1111/acel.12496/abstract.
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